An earlier analysis finished on European inhabitants steered variations in a selected phase of DNA, or genetic materials, is strongly related to severe COVID-19 an infection and hospitalisation.
This DNA phase is current in 50 per cent of South Asians as in comparison with 16 per cent of Europeans.
A group of scientists, led by Kumarasamy Thangaraj, from CSIR-Centre for Cellular and Molecular Biology (CCMB), Hyderabad and Professor Gyaneshwer Chaubey, from Banaras Hindu University (BHU), Varanasi, analysed the function of this DNA phase in figuring out COVID-19 outcomes among the South Asian inhabitants.
The discovering, revealed within the journal Scientific Reports on Friday, concluded that the genetic variants accountable for COVID-19 severity among Europeans might not play a task in illness susceptibility among South Asians.
“In this study, we have compared infection and case fatality rates with South Asian genomic data over three different timelines during the pandemic. We have especially looked into a large number of populations from India and Bangladesh,” Thangaraj.
“Our result reiterates the unique genetic origin of South Asian populations. A dedicated genome-wide association study on South Asian COVID-19 patients is the need of time for us in the Asian sub-continent,” stated Chaubey, first creator of the study.
The analysis additionally means that the genetic variants correlated with COVID-19 outcomes differ considerably among caste and tribal populations of Bangladesh.
“Scientists working in the area of population studies should be more cautious to interpret their findings by differentiating caste and tribal populations, more explicitly so in the Bangladeshi population,” stated Professor George van Driem, from The University of Bern in Switzerland.
“With growing data, it is becoming quite clear that there are several factors including genetics, immunity and the lifestyle are the contributing factor for COVID-19 susceptibility,” stated Driem, a co-author of the study.
Other members of this study included researchers from Dhaka University, Bangladesh, Forensic Science Laboratory in Madhya Pradesh, and Birla Institute of Scientific Research, Jaipur.